Integrated polymer chip for acoustic separation of Extracellular Vesicles
Setting the Scene
In a landscape buzzing with dynamic research and innovation, there's an unsung hero that could dramatically change the face of diagnostics and medical research: exosomes. These nanoscale vesicles are showing immense potential in an array of diagnostic applications across infectious diseases, cardiology, cancer, and more. However, a bottleneck hinders this rising star; isolating these microscopic workhorses from blood samples is labour-intensive and anything but straightforward. Cue AcouSome, an initiative by AcouSort to resolve this critical bottleneck and make exosome isolation efficient, automated, and precise.
The Innovation: AcouSome
AcouSome, an EIC Transition funded project, aims to marry acoustic separation with acoustic trapping into one seamless, automated chip-based platform. The technology leverages the proven acoustofluidic methods developed by Lund University to separate not only plasma from blood but also capture those elusive exosomes efficiently. While current technologies deploy mostly manual approaches that are expensive and unsuited for clinical-use applications, AcouSome ventures into cost-effective polymer chips that offer more stable performance at a fraction of the price.
Why AcouSome Stands Out
Efficiency & Purity: Isolate enough exosomes quickly and cleanly for detection and analysis.
Stability & Robustness: Reduce human error and variability to ensure reliable diagnostic outcomes.
Speed & Integration: Designed for rapid point-of-care testing and high-throughput lab