Integration of CMOS-based sensors, such as for DNA sequencing and organ-on-chip applications, enhances the capability to perform complex analyses directly on the chip. This integration allows the creation of hybrid microfluidic-CMOS platforms by combining fluidic structures with sensory elements.

Innovative Applications and Showcases:

• Diagnostic Device for Biomarker Detection: A stand-alone point-of-care product developed for use outside medical environments, integrating a CMOS sensor with a microfluidic flow cell.

• Organ-on-Chip Platform: A cell culture platform featuring a microfluidic well plate combined with a high-density multi-electrode array chip, enabling parallel testing of multiple samples.

• Water Quality Monitoring: A glass-silicon hybrid sensor chip for real-time monitoring of ions like chloride, sodium, nitrate, and calcium, demonstrating the practical application of integrated sensors in environmental monitoring.

Key Features:

• Enhances performance and adds critical functionalities to devices.

• Supports miniaturization and reduces the need for external hardware.

• Simplifies the user interface, making devices more intuitive and easier to handle in decentralized settings.

Electrode printing is pivotal in enhancing the electrical functionalities of microfluidic devices. Our advanced printing technologies allow for the precise deposition of conductive materials, forming highly effective electrodes that are integral to device operations.

Different Printing Technologies and Their Applications:

• Aerosol Jet Printing: Ideal for high-resolution, 3D substrate applications requiring precise conductive tracks.

• Inkjet Printing: Best suited for flexible, high-throughput production of electrodes on diverse substrates.

• Screen Printing: A cost-effective option for producing thicker electrode layers, offering robustness for industrial applications.

Key Features of Electrode Printing:

• Micron-scale precision ensuring optimal performance.

• Use of conductive inks for reliable electrical connections.

• Low-temperature processes  preserve the integrity of sensitive components.

• Customizable to fit specific design and functional needs of microfluidic devices.

By enhancing on-chip functionality, we concentrate complexity into the microfluidic platform, moving it away from peripheral equipment. Designed to integrate seamlessly into your systems, our sensors provide critical real-time data essential for diagnostics and analytical processes.

Different Sensor Types and Their Applications:

• Humidity Sensors: Perfect for environmental monitoring within microfluidic setups.

• Gas Sensors: Essential for detecting and measuring gases in chemical and biological analyses.

• pH Sensors: Crucial for monitoring the acidity or basicity in various diagnostic applications.

• Optical Sensors: Key for applications involving light detection and analysis, such as in optical density measurements and fluorescence-based assays.

• Voltage/Current Sensors: Thick film conductors for electrical impedance measurement, used in applications like electrical impedance spectroscopy chips and capillary electrophoresis chips.

• Temperature Sensors: Use of thermistors/thin film resistors, often in PCR assays.